Difference between revisions of "EQ Editor"

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=EQ Editor requirements=
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{{EventBox1|
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[[Phenex]] is our production EQ Editor.  This is an early requirements-gathering document and is out of date.  Feature requests for Phenex should be directed to the Phenex tracker, linked from the [[Phenex|Phenex homepage]].
 +
}}
  
The EQ Editor will be used by curators to annotate phenotypic descriptions of Ostariophysi using EQ syntax and ontologies.
+
=Overview=
 +
Currently, the EQ Editor is being developed by customizing [http://www.phenote.org/ Phenote] to our needs.  We are collaborating with the developers of Phenote at NCBO by contributing improvements to the core Phenote code, and we are also developing specialized components and configuration required for our annotation workflow.
  
The curator will use the EQ Editor to code phenotypic data from an existing publication into the EQ format.  This data consists of descriptions of character state values for corresponding species (or, more precisely, specimens).  A published character state description may contain: the species or higher taxonomic specification, a textual description of the character state value, reference to a voucher specimen for this description, an image showing the character.
+
=Requirements=
  
===Data Model===
+
These are the currently understood requirements - an earlier draft can be viewed at [[EQ Editor requirements draft 1]].
  
The following are essential data elements to be captured by the EQ Editor for each character state description (format is in parentheses).  There is some additional discussion of how to treat character definitions at [[EQ_for_character_matrices|"EQ for character matrices"]].
+
The EQ Editor will be used by curators to annotate phenotypic descriptions of Ostariophysi fish using EQ syntax and ontologies.
  
* species name (free text until taxonomic ontology is available?)
+
The curators will use the EQ Editor to code phenotypic data from an existing publication into the EQ format.  This data consists of descriptions of character state values for corresponding species (or, more precisely, specimens).  A published character state description may contain: the species or higher taxonomic specification, a textual description of the character state value, reference to a voucher specimen for this description, an image showing the character.
* voucher specimen lot ID (format?)
+
 
* specimen count
+
==Data Model==
* specimen preparation (cleared and stained, etc.)
+
 
 +
The following are essential data elements to be captured by the EQ Editor for each character state description (format is in parentheses).  EQ coding will be performed at the level of character states, but there may be a facility for dynamically viewing entries in a character matrix format.  See [[EQ_for_character_matrices|"EQ for character matrices"]] for a discussion - at the [[WG:PI_Meeting_5Jun07|June 5 PI meeting]] we decided to work with only character states.  Phenotype annotations should generally be made at the species taxonomic level.
 +
 
 +
===Phenotype Annotation===
 +
 
 +
* species name (ontology ID)
 
* EQ statement for character state (Q should be a value)
 
* EQ statement for character state (Q should be a value)
** E from fish anatomy (ontology ID)
+
** E from fish anatomy (ontology ID) - may be post-composed from multiple ontology terms, especially in conjunction with a spatial modifier ontology
 
** Q from PATO (ontology ID)
 
** Q from PATO (ontology ID)
** measurement (number) - used if Q is an attribute suitable for measurement (e.g. "length")
+
** measurement - used if Q is an attribute suitable for measurement (e.g. "length")
** measurement unit (units ontology ID)
+
*** number - should be able to put in single value, a range, or <, > ''- can all this be done within EQ formalism?''
 +
*** unit (units ontology ID)
 
** E2 from fish anatomy (if Q is descendant of "relational quality of continuant" or "relational quality of occurrent") (ontology ID)
 
** E2 from fish anatomy (if Q is descendant of "relational quality of continuant" or "relational quality of occurrent") (ontology ID)
* original description (free text)
+
* textual description (free text)
 
* publication/citation (DOI? older publications don't have DOI, do they? Another possibility is [http://iphylo.blogspot.com/2007/05/openurl-and-spiders.html SICI])
 
* publication/citation (DOI? older publications don't have DOI, do they? Another possibility is [http://iphylo.blogspot.com/2007/05/openurl-and-spiders.html SICI])
* image or URL for image (image data or URL)
+
* Reference to section, figure, or image from publication (free text)
* evidence statement (confirmation by taxonomic expert, etc.) ''- this requires discussion''
+
* Evidence code (''the list of evidence codes requires discussion'')
 +
** Specimen catalog number(s) supporting evidence code when required (direct observation)
  
===Workflow===
+
===Additional data per publication===
  
====Sources of data====
+
Some data from the publications may be useful to store in our database, independent of phenotype annotations.
 +
* Entire specimen list (catalog numbers) in publication materials.  This could be useful to users of the site who may want to see what specimens the author was using, even if the annotated phenotypes were not explicitly tied to a catalog number.  Further, we could use the catalog numbers to access museum specimen data services for various future applications.
 +
 
 +
==Workflow==
 +
 
 +
===Sources of data===
  
 
The publication being coded may contain data in one of a few different formats.  The given data format may suggest its own style of workflow.  These publication types include 3 main forms:
 
The publication being coded may contain data in one of a few different formats.  The given data format may suggest its own style of workflow.  These publication types include 3 main forms:
Line 34: Line 49:
 
# A single species description of values for many characters.
 
# A single species description of values for many characters.
 
# Description of a single character for many species (perhaps less common than the other formats?).  If focusing on a single character the data may come from multiple publications.
 
# Description of a single character for many species (perhaps less common than the other formats?).  If focusing on a single character the data may come from multiple publications.
 
  
 
It seems like scenarios 2 and 3 can be treated as special cases of scenario 1.  For each character, an interface is required for choosing the Entity and Quality from their respective ontologies, and entering free text such as the original character descriptions, as well as other [[#Data_Model|relevant data]].
 
It seems like scenarios 2 and 3 can be treated as special cases of scenario 1.  For each character, an interface is required for choosing the Entity and Quality from their respective ontologies, and entering free text such as the original character descriptions, as well as other [[#Data_Model|relevant data]].
  
====Detailed steps====
+
===Detailed steps===
  
 
The standard workflow would be a curator dealing with a single publication during a session of working with the EQ Editor.  Steps might be:
 
The standard workflow would be a curator dealing with a single publication during a session of working with the EQ Editor.  Steps might be:
Line 45: Line 59:
 
# Enter document-wide data:
 
# Enter document-wide data:
 
## publication information (author, title, journal)
 
## publication information (author, title, journal)
## list of specimens - input specimen info and choose taxon from taxonomic ontology for each one
+
## list of species - choose taxon from taxonomic ontology for each one
 +
##* For each species, input list of specimen catalog numbers used in the publication, choosing museum institutions from a pick list
 
# Begin making character state annotations:
 
# Begin making character state annotations:
## Select a specimen or multiple specimens to which this character state applies (there should be facilities for efficiently choosing sets of specimens/taxa)
+
## Select a species or multiple species to which this character state applies (there should be facilities for efficiently choosing sets of taxa)
 +
##* If the author makes a statement about a higher taxon (e.g. a family), make a phenotype annotation for every species in the materials list for that publication which is a member of the taxon.
 
## Create a new EQ statement
 
## Create a new EQ statement
 
## Choose Entity from anatomy ontology
 
## Choose Entity from anatomy ontology
Line 53: Line 69:
 
## If the Quality is an Attribute term (such as "length"), enter a measurement and its units
 
## If the Quality is an Attribute term (such as "length"), enter a measurement and its units
 
## If the Quality is relational, enter a second Entity from the anatomy ontology
 
## If the Quality is relational, enter a second Entity from the anatomy ontology
## If dealing with a single specimen, enter optional image data (URL). Images may not be applied to multiple specimens at once.
+
## Enter the evidence code appropriate for the published statement - if the phenotype is clearly based on one or more specific specimen numbers, enter them into the catalog number(s) field to support the appropriate evidence code.
# At any point, the curator can save the current work to a document (or database).  We should investigate requirements regarding the document format (relationship to PhenoXML/PhenoSyntax, NEXUS, etc.), which will depend on the detailed data model.
+
## Enter any information for the figure or section within the paper showing the character.
 +
# At any point, the curator can save the current work to a document (or database).
  
====Working with EQ statements====
+
===Working with EQ statements===
* A particular EQ statement (specific combination of Entity and Quality) will often be applied to multiple specimens within one document.  Specimens are likely to share EQ values as a result of phylogenetic history, so facilities for efficiently selecting groups of related specimens should be available.  Entries with this EQ statement would be generated for each selected specimen.
+
* A particular EQ statement (specific combination of Entity and Quality) will often be applied to multiple species within one document.  Species are likely to share EQ values as a result of phylogenetic history, so facilities for efficiently selecting groups of related species should be available.  Entries with this EQ statement would be generated for each selected species.
** An EQ entry panel could allow the user to choose a taxon from the taxonomic ontology, either by directly browsing the ontology or through an autocomplete text search field.  All specimens within that taxon would be selected.
+
** An EQ entry panel could allow the user to choose a taxon from the taxonomic ontology, either by directly browsing the ontology or through an autocomplete text search field.  All species within that taxon would be selected.
** A phylogenetic tree view could be provided, which allows the user to select a node or nodes to which to apply an EQ statement.  All specimens descending from that node would be selected.  This tree could be initialized by using the taxonomic ontology.  The user could manually edit the tree to provide additional resolution (perhaps by following a tree in the paper).  Alternatively, the software could allow the specification in Newick format of a tree created by another application.
+
** A phylogenetic tree view could be provided, which allows the user to select a node or nodes to which to apply an EQ statement.  All species descending from that node would be selected.  This tree could be initialized by using the taxonomic ontology.  The user could manually edit the tree to provide additional resolution (perhaps by following a tree in the paper).  Alternatively, the software could allow the specification in Newick format of a tree created by another application.
 
** It would be useful to be able to invert selections generated by either of the preceding methods.
 
** It would be useful to be able to invert selections generated by either of the preceding methods.
 +
* The EQ statements entered into the document should be able to be viewed in various ways to allow checking data entry progress.  Various views are desired:
 +
** Flat list of all entered EQ statements.
 +
** Filtered flat list - a search text field can allow quick filtering by any of the data fields.
 +
** Character-by-taxon matrix - generated from EQ statements by grouping via shared PATO Attributes.
 +
** Filtered matrix view - what capabilities are needed?  filter by taxon, entity, quality: if one of these is a higher term in the ontology, show all descendant matches
  
====Questions====
+
===Questions===
  
 
* What should the user be able to do if there is not an appropriate term in the ontology?
 
* What should the user be able to do if there is not an appropriate term in the ontology?
 +
* Need to add a button to say "Need a new term"
 
* What will be done (in the immediate term) with the annotations produced by the EQ Editor?  Will they be stored in separate documents, or compiled into a central repository?
 
* What will be done (in the immediate term) with the annotations produced by the EQ Editor?  Will they be stored in separate documents, or compiled into a central repository?
* Is a "post-composition" capability required?
 
* Need to add a button to say "Need a new term"
 
  
===Technology===
 
  
Some technology choices may figure into the application requirements, particularly if integration with another application or system is a desired feature.  Possibilities include:
+
=Roadmap=
* Implement EQ editing as a Mesquite plug-in, providing some additional interface to the character editing already in Mesquite.  This would require extensions to the NEXUS format for storing ontology term information. Here is [[Mesquite|some more discussion on Mesquite]].
+
 
* Extending [http://www.phenote.org/ Phenote] with any additional functionality that is required.  Phenote is being actively developed by the model organism community, but deals with a list of unordered EQ statements rather than a species-by-character matrix.  Here is [[Phenote|some more discussion on Phenote]].
+
See the [[software roadmap]] for further plans.
* Web-based application.
+
 
* Components from all of the above.
+
[[Category:Informatics]]

Latest revision as of 17:54, 5 November 2008

Phenex is our production EQ Editor. This is an early requirements-gathering document and is out of date. Feature requests for Phenex should be directed to the Phenex tracker, linked from the Phenex homepage.

Overview

Currently, the EQ Editor is being developed by customizing Phenote to our needs. We are collaborating with the developers of Phenote at NCBO by contributing improvements to the core Phenote code, and we are also developing specialized components and configuration required for our annotation workflow.

Requirements

These are the currently understood requirements - an earlier draft can be viewed at EQ Editor requirements draft 1.

The EQ Editor will be used by curators to annotate phenotypic descriptions of Ostariophysi fish using EQ syntax and ontologies.

The curators will use the EQ Editor to code phenotypic data from an existing publication into the EQ format. This data consists of descriptions of character state values for corresponding species (or, more precisely, specimens). A published character state description may contain: the species or higher taxonomic specification, a textual description of the character state value, reference to a voucher specimen for this description, an image showing the character.

Data Model

The following are essential data elements to be captured by the EQ Editor for each character state description (format is in parentheses). EQ coding will be performed at the level of character states, but there may be a facility for dynamically viewing entries in a character matrix format. See "EQ for character matrices" for a discussion - at the June 5 PI meeting we decided to work with only character states. Phenotype annotations should generally be made at the species taxonomic level.

Phenotype Annotation

  • species name (ontology ID)
  • EQ statement for character state (Q should be a value)
    • E from fish anatomy (ontology ID) - may be post-composed from multiple ontology terms, especially in conjunction with a spatial modifier ontology
    • Q from PATO (ontology ID)
    • measurement - used if Q is an attribute suitable for measurement (e.g. "length")
      • number - should be able to put in single value, a range, or <, > - can all this be done within EQ formalism?
      • unit (units ontology ID)
    • E2 from fish anatomy (if Q is descendant of "relational quality of continuant" or "relational quality of occurrent") (ontology ID)
  • textual description (free text)
  • publication/citation (DOI? older publications don't have DOI, do they? Another possibility is SICI)
  • Reference to section, figure, or image from publication (free text)
  • Evidence code (the list of evidence codes requires discussion)
    • Specimen catalog number(s) supporting evidence code when required (direct observation)

Additional data per publication

Some data from the publications may be useful to store in our database, independent of phenotype annotations.

  • Entire specimen list (catalog numbers) in publication materials. This could be useful to users of the site who may want to see what specimens the author was using, even if the annotated phenotypes were not explicitly tied to a catalog number. Further, we could use the catalog numbers to access museum specimen data services for various future applications.

Workflow

Sources of data

The publication being coded may contain data in one of a few different formats. The given data format may suggest its own style of workflow. These publication types include 3 main forms:

  1. Description of many characters for many species and higher taxonomic levels; no character-by-taxon matrix published.
  2. A data matrix with multiple species and multiple characters. There is a character state value for each cell in this matrix.
  3. A single species description of values for many characters.
  4. Description of a single character for many species (perhaps less common than the other formats?). If focusing on a single character the data may come from multiple publications.

It seems like scenarios 2 and 3 can be treated as special cases of scenario 1. For each character, an interface is required for choosing the Entity and Quality from their respective ontologies, and entering free text such as the original character descriptions, as well as other relevant data.

Detailed steps

The standard workflow would be a curator dealing with a single publication during a session of working with the EQ Editor. Steps might be:

  1. Create a new EQ Editor document.
  2. Enter document-wide data:
    1. publication information (author, title, journal)
    2. list of species - choose taxon from taxonomic ontology for each one
      • For each species, input list of specimen catalog numbers used in the publication, choosing museum institutions from a pick list
  3. Begin making character state annotations:
    1. Select a species or multiple species to which this character state applies (there should be facilities for efficiently choosing sets of taxa)
      • If the author makes a statement about a higher taxon (e.g. a family), make a phenotype annotation for every species in the materials list for that publication which is a member of the taxon.
    2. Create a new EQ statement
    3. Choose Entity from anatomy ontology
    4. Choose Quality from PATO (usually a Value term)
    5. If the Quality is an Attribute term (such as "length"), enter a measurement and its units
    6. If the Quality is relational, enter a second Entity from the anatomy ontology
    7. Enter the evidence code appropriate for the published statement - if the phenotype is clearly based on one or more specific specimen numbers, enter them into the catalog number(s) field to support the appropriate evidence code.
    8. Enter any information for the figure or section within the paper showing the character.
  4. At any point, the curator can save the current work to a document (or database).

Working with EQ statements

  • A particular EQ statement (specific combination of Entity and Quality) will often be applied to multiple species within one document. Species are likely to share EQ values as a result of phylogenetic history, so facilities for efficiently selecting groups of related species should be available. Entries with this EQ statement would be generated for each selected species.
    • An EQ entry panel could allow the user to choose a taxon from the taxonomic ontology, either by directly browsing the ontology or through an autocomplete text search field. All species within that taxon would be selected.
    • A phylogenetic tree view could be provided, which allows the user to select a node or nodes to which to apply an EQ statement. All species descending from that node would be selected. This tree could be initialized by using the taxonomic ontology. The user could manually edit the tree to provide additional resolution (perhaps by following a tree in the paper). Alternatively, the software could allow the specification in Newick format of a tree created by another application.
    • It would be useful to be able to invert selections generated by either of the preceding methods.
  • The EQ statements entered into the document should be able to be viewed in various ways to allow checking data entry progress. Various views are desired:
    • Flat list of all entered EQ statements.
    • Filtered flat list - a search text field can allow quick filtering by any of the data fields.
    • Character-by-taxon matrix - generated from EQ statements by grouping via shared PATO Attributes.
    • Filtered matrix view - what capabilities are needed? filter by taxon, entity, quality: if one of these is a higher term in the ontology, show all descendant matches

Questions

  • What should the user be able to do if there is not an appropriate term in the ontology?
  • Need to add a button to say "Need a new term"
  • What will be done (in the immediate term) with the annotations produced by the EQ Editor? Will they be stored in separate documents, or compiled into a central repository?


Roadmap

See the software roadmap for further plans.