Training and Workshops

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Evolution 2017 SSB workshop – Trees, traits and functions: semantics for comparative biology

Day: Friday, June 23, 2017
Time: 1:30 PM - 5:00 PM
Location: Oregon Convention Center, Portland, Rm. B114
An optional pre-conference event. Prior registration required (during conference registration).

Topic: A rich set of comparative phylogenetic methods has been developed in recent decades for the analysis of traits, functions, and other macroevolutionary patterns. A similarly rich set of tools, such as ontologies, data annotation models, and machine reasoners, have also recently been introduced allowing researchers to represent the semantics of phenotypes, traits, functions, and environmental properties in such a way that computers can access what had previously been the implicit knowledge of biological experts. Although these two efforts have remained largely separate from each other, a few studies at their intersection have shown that their synthesis has the potential to enable new classes of comparative analyses and provide an interdisciplinary bridge between different phylogenetics user communities. This symposium brings together research at the nexus of comparative phylogenetics and computable semantics of biological knowledge. The aim is to stimulate discussion and awareness of the opportunities that are emerging for the comparative biology community.

Speakers:

  • Carrine Blank (U. Montana) Use of natural language processing algorithms, ontologies, and phylogenomic trees to automate and accelerate phenotypic trait evolutionary studies for prokaryotes
  • Paula Mabee (U. South Dakota) Progress in comparative biology can be accelerated through semantic annotation
  • Paul Thomas (U. Southern California) Modeling the evolution of gene function using phylogenies and the Gene Ontology
  • Martin Ramirez (Museo Argentino de Ciencias Naturales) Tracing the evolution of complex traits: the integration of atomized morphological data on phylogenies
  • Sergei Tarasov (NIMBioS, U. Tennessee, Knoxville) Anatomy Ontology, Bayesian Networks and Evo-Devo suggest a new framework for modeling discrete morphological characters
  • Josef Uyeda (Virginia Tech U.) Can ontologies help understand trait evolution (and vice versa)?

Workshop on New Tools for Studying Phenotype Evolution in the Vertebrates, February 7-10, 2013

What new research opportunities are opened up by the power to compute over phenotype information from thousands of species of vertebrates, together with phenotype and expression information for thousands of genes in multiple model organisms? The first release of the Phenoscape Knowledgebase includes over 500K species phenotypes linked to 4,000+ genes from zebrafish, and is currently being extended to capture phenotype data from other vertebrates and linked to phenotype and expression data for other model organisms (including mouse and Xenopus). Scientists were invited through an open call and invitations to participate in a workshop facilitated by KnowInnovation, with the aim of initiating new collaborations to drive the development of the Phenoscape tool set/interface and present new and creative ways to deepen understanding of phenotypic evolution. We were particularly interested in a broad approach to this problem and welcomed scientists with backgrounds in computational and systems biology, mathematics, development, genomics, and evolution. Phenoscape is supporting the initial steps in projects that were the outcome of this successful workshop. Supplemental funding for facilitation was generously awarded from the National Science Foundation. Funding for participation of ichthyologists in this workshop was provided by the DeepFin Research Coordination Network. Location: California Academy of Sciences. Organizers: David Blackburn, Paula Mabee and Todd Vision, together with KnowInnovation.

Anatomy Ontology Summer Course: July 30 to August 3, 2012

A summer course on anatomy ontologies was offered in Durham NC, made possible by the NESCent Academy and the Phenotype Ontology Research Coordination Network.

PATO workshop: September 25-27, 2010

Members of Phenoscape met with personnel from the Hymenoptera Anatomy Ontology (HAO) project, TAIR and the Phenotype and Trait Ontology (PATO) at the University of Oregon to discuss and find solutions to reasoning issues that have arisen as a result of PATO ontology structure, and ways to represent phenotypes using the EQ model.

Skeletal Anatomy Jamboree: April 9-10, 2010

The meeting focused on re-evaluating the high-level skeletal system ontology hierarchy for fishes, particularly in relation to anatomy ontologies of other vertebrates. Participants re-examined existing terms and definitions (cells, tissues, development, anatomical structures) for their applicability across vertebrates, and discussed how to represent of bone development within the structurally-defined hierarchy.

Workshop @ The Field Museum: March 19, 2010

The purpose of this meeting was outreach and training to local morphologists at the Field Museum and University of Chicago, informal usability testing of Phenoscape Knowledgebase interface, and to conduct a Phenoscape project meeting.

Ontologies for Ichthyology and Herpetology: July 25, 2009

Asih2009ontologyworkshop.png

Organizers:

  • Paula Mabee, Professor, Dept. of Biology, University of South Dakota
  • Anne Maglia, Professor, Missouri University of Science and Technology
  • Todd Vision, Assistant Director, National Evolutionary Synthesis Center (NESCent) and Associate Professor, Dept. of Biology, University of North Carolina
  • Monte Westerfield, Director, Zebrafish Information Network and Professor, Institute of Neuroscience, University of Oregon

The aim of this workshop to promote the integration of ichtyological and herpetological data with genetic, genomic, and developmental data for the purposes of understanding the genetic basis for phenotypic variation and diversification. The focus will be on major anatomical ontology efforts already underway in these organisms, and their use within new and existing morphological databases.

While knowledge from model organism biology can inform our understanding of natural phenotypic variation and evolution, differing vocabularies and scientific cultures make it difficult for individuals to find the latent connections between these two fields. Ontologies, controlled vocabularies with well-defined relations among terms, are a key tool in scientific data integration; by using ontologies, scientists from different disciplines can know when they are referring to the same entity by different names, and new discoveries are enabled by computer software being able to reason across disciplines and over large datasets. Already widely used in genomics, ontologies are of growing importance in systematics, ecology, behavior, genetics, morphology and physiology. This workshop aims to explore the utility of ontologies for ichthyology and herpetology, using the Teleost Anatomy Ontology and the Amphibian Anatomy Ontology as case studies of community resources that are being actively developed and used by members of ASIH. Participants will present examples of how these ontologies are being used to address novel research questions in the evolutionary of phenotype using model organism data, and to provide new ways of exploring data within morphological databases.

More information here.

Phenotype Ontology Coordination Workshop: April 27-28, 2009

The goal of this workshop was to discuss plans for an RCN (Research Coordination Network) or INTEROP (Community-based Data Interoperability Networks) application to NSF that we would submit in July or August 2009.

Evolutionary Biology and Ontologies Workshop II: January 5, 2009

This workshop will be held in conjunction with the 2009 SICB Annual Meeting in Boston, MA, in the morning of January 5, 2009. It is cosponsored by the National Evolutionary Synthesis Center (NESCent) and the National Center for Biomedical Ontologies (NCBO).

Organizers
Paula Mabee (U. South Dakota), Barry Smith (SUNY Buffalo), Todd Vision (UNC Chapel Hill, NESCent), Monte Westerfield (U. Oregon, ZFIN)
Goals
The workshop is focused on the application of ontologies to studies in comparative biology, with a particular emphasis on morphological and behavioral phenotypes. The goal is to introduce what ontologies are, how they are built, what makes an ontology useful, how ontologies can help researchers collaborate across disciplines, and to highlight several applications of this approach to comparative biology.
Registration
Registration is open to attendees of the SICB 2009 conference at no additional cost.

Further information can be found at the workshop page at the NCBO wiki. There is also a workshop abstract for dissemination at the SICB website or as a single-page flyer in PDF. Please feel free to distribute the link to your colleagues and students.

Presentations

  • Barry Smith - An introduction to ontologies for evolutionary biologists
  • Monte Westerfield - Linking animal models and human diseases
  • Paula Mabee - Phenoscape: extending model organism ontologies for devo-studies of evolutionary phenotypes
  • Wasila Dahdul - Challenges of developing multi-species anatomy ontologies
  • Todd Vision - Software and database resources for curation and management of evolutionary phenotypes
  • Andy Deans - Developing a Hymenopteran ontology
  • Peter Midford - Comparative Analysis of behavior using ontologies
  • Anne Maglia - Developing an amphibian ontology

Second Data Roundup: September 28-October 1, 2008

The second Morphology Data Jamboree, later renamed to Data Roundup, took place in Rapid City and Sylvan Lake Lodge, South Dakota, and included project personnel, affiliated curators, and external advisors.

Evolutionary Biology and Ontologies Workshop I: June 20, 2008

Evolution2008-OntologyWorkshop.png

This workshop will be held in conjunction with the Evolution 2008 meeting in Minneapolis, MN, 20 June 2008. It is organized under the auspices of the National Center for Biomedical Ontologies (NCBO) in collaboration with the National Evolutionary Synthesis Center (NESCent).

Organizers
Barry Smith (Buffalo), Paula Mabee (University of South Dakota), Todd Vision (University of North Carolina, Chapel Hill), Monte Westerfield (University of Oregon)
Focus
This meeting is focused on the application of ontologies to studies in evolutionary biology and related disciplines, with a particular emphasis on studies of the phenotype.
Goals
  1. Introducing what ontologies are, how they should be built, what makes an ontology useful, and how ontologies help people collaborate across disciplines;
  2. Giving illustrations of ontologies actually being used to address problems of interest to evolutionary biologists;
  3. Networking and planning: what do we do next in order to advance ontology-based information integration in evolutionary biology?
Registration
Registration will be open to attendees of the Evolution 2008 conference at no additional cost.

Further information can be found at the workshop page at the NCBO wiki. There is also a workshop flier for dissemination. Please feel free to distribute the flier to your colleagues and students.

Presentations

First Morphology Data Jamboree: April 18-20, 2008

The first Data Jamboree on Morphology with project personnel, affiliated ichthyologists and curators, and external advisors was held at NESCent on April 18-20, 2008.

Needs Analysis Workshop: September 17-18, 2007

The Needs Analysis Workshop brought together leading scientists from the fields of morphology, development, evolution, genetics, and ichthyology to identify driving biological research questions that take the most advantage of the evolutionary, anatomical, developmental, and genetics data that the Phenoscape will integrate. In particular, the workshop aimed to identify what informatic tools are needed in order to answer those questions. The workshop was held at NESCent on September 17-18, 2007.

Summer Training Opportunities

Opportunities in summer 2009 are available to graduate students and postdocs for training in data curation and software development at NESCent and the University of South Dakota. More information.