Difference between revisions of "Phenotype Ontology Coordination Workshop"
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− | <center><big>'''Phenotype Ontology Coordination Workshop'''</big><br/><br/>A workshop hosted by the National Evolutionary Synthesis Center (NESCent) | + | <center><big>'''Phenotype Ontology Coordination Workshop: April 27-28, 2009'''</big><br/><br/>A workshop hosted by the National Evolutionary Synthesis Center (NESCent)</center> |
+ | __NOTOC__ | ||
+ | <div style="float: right;">__TOC__</div> | ||
== Location and Date == | == Location and Date == | ||
'''Venue:''' National Evolutionary Synthesis Center (NESCent) (<span class="plainlinks">[http://www.nescent.org/about/directions.php directions]</span>, also see <span class="plainlinks">[http://www.nescent.org/about/information.php information for visitors]</span>) | '''Venue:''' National Evolutionary Synthesis Center (NESCent) (<span class="plainlinks">[http://www.nescent.org/about/directions.php directions]</span>, also see <span class="plainlinks">[http://www.nescent.org/about/information.php information for visitors]</span>) | ||
− | '''Date:''' | + | '''Date:''' April 27-28, 2009 |
'''Organizers:''' Paula Mabee, Monte Westerfield, Todd Vision | '''Organizers:''' Paula Mabee, Monte Westerfield, Todd Vision | ||
Line 11: | Line 13: | ||
== Introduction == | == Introduction == | ||
+ | The goal of this workshop is to discuss plans for an [http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=11691 RCN (Research Coordination Network)] or [http://www.nsf.gov/pubs/2007/nsf07565/nsf07565.htm INTEROP (Community-based Data Interoperability Networks)] application to NSF that we would submit in July or August 2009. The grant would provide funds for 3-5 years of meetings and workshops (and in the case of the INTEROP program, implementation to a limited extent) to identify problems and develop methods and plans to describe phenotypes in a much broader range of species. | ||
+ | |||
+ | Specific goals are to be determined by the workshop participants. An initial list includes establishing and maintaining communication among evolutionary biologists and model organism communities developing ontologies, coordinating efforts among the broader ontology community so that these ontologies are interoperable, and methods to align and reason across multi-species ontologies for phenotype and taxonomy. The workshop includes interested members from both the model organism and evolutionary biology communities. | ||
== Agenda == | == Agenda == | ||
+ | === Monday, Apr. 27, 2009 === | ||
+ | |||
+ | ''Taking stock: Where do we stand? What resources and needs do we have in common? Identify broader community needs for a [Comparative Evolutionary] Phenotype Consortium that are not currently served by individual grants.'' | ||
+ | |||
+ | '''Morning:''' What new ontologies are required? How do existing common ontologies need to be extended? | ||
+ | |||
+ | * 8:00 SHUTTLE FROM HOTEL | ||
+ | * 8:15 Coffee & pastries | ||
+ | * 8:30-9:30 Welcomes from NESCent (Todd Vision) and participant introductions (2-3 minute lightening talks) | ||
+ | * 9:30-9:45 Paula Mabee: Introduction | ||
+ | * 9:45 Breakout groups (4 groups, all 4 questions each): | ||
+ | * Breakout questions: Tools (software), standards, and ontologies | ||
+ | * 1. What are the key gaps in tools to develop your work? | ||
+ | * 2. What are key obstacles to data exchange and data integration? | ||
+ | * 3. What do you perceive as the key ontologies that are lacking? | ||
+ | * 4. What are the gaps in expertise in understanding, developing and applying ontologies in the community? | ||
+ | * 10:45 Coffee | ||
+ | * 11:00-11:45 Second breakout (2 groups, 2 questions each) | ||
+ | * 11:45-12:15 Reports from break-out groups | ||
+ | * 12:15 LUNCH | ||
+ | |||
+ | '''Afternoon:''' Annotation and Interoperability | ||
+ | |||
+ | * 1:30 – 2:00: Case study and analysis; interoperability (Monte Westerfield) | ||
+ | * 2:00 – 2:45: Breakout groups: | ||
+ | *# Annotation group: What phenotype curation/annotation needs are there that are not adequately met? E.g. software, standards, best-practices, education, syntax, etc. | ||
+ | *# Interoperability group 1 (MOD-EvoD): Develop a plan for interoperability between MODs and EvoDs through ontology synchronization and alignment | ||
+ | *# Interoperability group 2 (EvoD-EvoD): Develop a plan for interoperability among EvoDs, and with other community resources through alignment, considering the types of driving research questions (similarity searches on function, homology, etc.). What are the most important databases and tools to integrate into this effort? | ||
+ | * 2:45-3:15 Group reports | ||
+ | * 3:15 Coffee break | ||
+ | * 3:30-4:15: Annotation, Interoperability I and II break out groups (different participants) | ||
+ | * 4:15-5:00: Reports from break outs and discussion | ||
+ | * 5:00: Van back to hotel | ||
+ | * 5:30-6:30: Drinks at hotel | ||
+ | * 6:30 Van from hotel to dinner (whole group) | ||
+ | === Tuesday, Apr. 27, 2009 === | ||
+ | |||
+ | '''Morning:''' Databases and Trees; | ||
+ | |||
+ | * 8:00 SHUTTLE FROM HOTEL | ||
+ | * 8:15 Coffee & pastries | ||
+ | * 8:45 – 9:30 Break out groups | ||
+ | *# Database group: Do we have database needs for annotations from this grant activity? Common database, i.e. a vision to create a community resource for comparative phenotype data? | ||
+ | *# Tree group: How does phylogenetic tree inference vs. mapping intersect with the needs of a phenotype consortium? | ||
+ | *# Outreach group: What are the priority outreach elements from this grant? How to make these ontologies and annotations (?) available to the broader community? Training (e.g. summer course at Biosynthesis Center, CSH, NESCent, NCESC? Other?); Develop online tutorials? Infrastructure for basics: mailing list, meeting announcements, etc. | ||
+ | * 9:30-10:00 Reports from break out groups | ||
+ | * 10:00-10:15 Coffee | ||
+ | * 10:15-10:30: Decisions on who will write up break out group ideas | ||
+ | * 10:30-11:30: Writing | ||
+ | * 11:30-12:00: Action items, plans, preliminary coordination of grant proposal | ||
+ | * 12:00 Lunch, participants leave | ||
== Logistics == | == Logistics == | ||
Line 23: | Line 79: | ||
== Reading == | == Reading == | ||
− | * | + | * Within the Phenoscape project, we have been tagging interesting references about phenotype and taxonomy ontologies by using the tag "<span class="plainlinks">[http://www.connotea.org/tag/phenoscape phenoscape]</span>" on Connotea. Everyone is welcome to suggest references by using this tag. |
− | + | <!--# Mabee PM, Ashburner M, Cronk Q, Gkoutos GV, Haendel M, Segerdell E, Mungall C, and Westerfield M. Phenotype ontologies: the bridge between genomics and evolution. Trends Ecol Evol 2007 Jul; 22(7) 345-50. [http://dx.doi.org/10.1016/j.tree.2007.03.013 doi:10.1016/j.tree.2007.03.013] | |
− | # Mabee PM, Ashburner M, Cronk Q, Gkoutos GV, Haendel M, Segerdell E, Mungall C, and Westerfield M. Phenotype ontologies: the bridge between genomics and evolution. Trends Ecol Evol 2007 Jul; 22(7) 345-50. [http://dx.doi.org/10.1016/j.tree.2007.03.013 doi:10.1016/j.tree.2007.03.013] | ||
# Mabee PM, Arratia G, Coburn M, Haendel M, Hilton EJ, Lundberg JG, Mayden RL, Rios N, and Westerfield M. Connecting evolutionary morphology to genomics using ontologies: a case study from Cypriniformes including zebrafish. J Exp Zoolog B Mol Dev Evol 2007 Jun 28. [http://dx.doi.org/10.1002/jez.b.21181 doi:10.1002/jez.b.21181] | # Mabee PM, Arratia G, Coburn M, Haendel M, Hilton EJ, Lundberg JG, Mayden RL, Rios N, and Westerfield M. Connecting evolutionary morphology to genomics using ontologies: a case study from Cypriniformes including zebrafish. J Exp Zoolog B Mol Dev Evol 2007 Jun 28. [http://dx.doi.org/10.1002/jez.b.21181 doi:10.1002/jez.b.21181] | ||
− | # Haendel, M.A., Neuhaus, F., Osumi-Sutherland, D.S., Mabee, P.M., Mejino J.L.V., Mungall, C.J., and Smith, B. (2008) [[Media:Caroreprint.pdf|CARO - The Common Anatomy Reference Ontology]]. ''In:'' Albert Burger, Duncan Davidson and Richard Baldock (Editors): ''Anatomy Ontologies for Bioinformatics: Principles and Practice''. ISBN 978-1-84628-884-5. | + | # Haendel, M.A., Neuhaus, F., Osumi-Sutherland, D.S., Mabee, P.M., Mejino J.L.V., Mungall, C.J., and Smith, B. (2008) [[Media:Caroreprint.pdf|CARO - The Common Anatomy Reference Ontology]]. ''In:'' Albert Burger, Duncan Davidson and Richard Baldock (Editors): ''Anatomy Ontologies for Bioinformatics: Principles and Practice''. ISBN 978-1-84628-884-5.--> |
+ | |||
+ | == Final report == | ||
+ | * The [[Media:Phenotype_mtgreport.pdf|final report]] from this workshop summarizes the participants views as the specific research questions to be answered and thus goals to be achieved through a community‐based grant. Break-out groups provided perspective on the questions below. | ||
+ | 1. What are the key gaps in tools to develop your work? | ||
+ | 2. What are key obstacles to data exchange and data integration? | ||
+ | 3. What do you perceive as the key ontologies that are lacking? | ||
+ | 4. What are the gaps in expertise in understanding, developing and applying | ||
+ | ontologies in the community? | ||
== Participants == | == Participants == | ||
− | Members of | + | Members of Phenoscape are in '''bold font'''. |
{| border="1" cellpadding="3" cellspacing="0" | {| border="1" cellpadding="3" cellspacing="0" | ||
|- | |- | ||
! Name !! Institution | ! Name !! Institution | ||
− | {{EventParticipant| | + | {{EventParticipant|Blake|Judy|Judith%2eBlake%40jax%2eorg|The Jackson Laboratory |}} |
− | {{EventParticipant|Lapp|Hilmar|hlapp%40nescent%2eorg|NESCent|'''}} | + | {{EventParticipant|Coddington|Jonathan|CODDINGTON%40si%2eedu|Department of Entomology, Smithsonian Institution|}} |
− | {{EventParticipant| | + | {{EventParticipant|Cowell|Lindsay|lgcowell%40duke%2eedu|Duke University Medical Center |}} |
− | {{EventParticipant|Mabee|Paula|pmabee%40usd%2eedu|University of South Dakota|'''}} | + | {{EventParticipant|Deans|Andy|andy_deans%40ncsu%2eedu|Hymenoptera Tree of Life and Department of Entomology, North Carolina State University|}} |
− | {{EventParticipant|Midford|Peter| | + | {{EventParticipant|Dumont|Betsy|bdumont%40bio%2eumass%2eedu|Department of Biology, Univerity of Massachusetts, Amherst|}} |
− | {{EventParticipant|Vision|Todd|tjv%40bio%2eunc%2eedu|NESCent, and Department of Biology, University of North Carolina at Chapel Hill|'''}} | + | {{EventParticipant|Huala|Eva|huala%40acoma%2estanford%2eedu|The Arabidopsis Information Resource|}} |
− | {{EventParticipant|Westerfield|Monte|monte%40uoneuro%2euoregon%2eedu|Zebrafish Information Network (ZFIN) and Institute of Neuroscience, University of Oregon|'''}} | + | {{EventParticipant|Lapp|Hilmar|hlapp%40nescent%2eorg|Phenoscape and NESCent|'''}} |
+ | {{EventParticipant|Lewis|Suzi|suzi%40berkeleybop%2eorg|Berkeley Bioinformatics and Ontology Project |}} | ||
+ | {{EventParticipant|Mabee|Paula|pmabee%40usd%2eedu|Phenoscape and Department of Biology, University of South Dakota|'''}} | ||
+ | {{EventParticipant|Maglia|Anne|magliaa%40mst%2eedu|Missouri University of Science and Technology|}} | ||
+ | {{EventParticipant|Mast|Austin|amast%40bio%2efsu%2eedu|Florida State University|}} | ||
+ | {{EventParticipant|Midford|Peter|peter%2emidford%40gmail%2ecom| Phenoscape and Dept. of Ecology and Evolutionary Biology, University of Kansas|'''}} | ||
+ | {{EventParticipant|Parr|Cyndy|csparr%40gmail%2ecom |Smithsonian Institution and Encyclopedia of Life|}} | ||
+ | {{EventParticipant|Riccardi|Greg|riccardi%40ci%2efsu%2eedu|College of Information, Florida State University|}} | ||
+ | {{EventParticipant|Sereno|Paul|dinosaur%40uchicago%2eedu|University of Chicago|}} | ||
+ | {{EventParticipant|Stoltzfus|Arlin|stoltzfu%40umbi%2eumd%2eedu|Center for Advanced Research in Biotechnology, University of Maryland|}} | ||
+ | {{EventParticipant|Vision|Todd|tjv%40bio%2eunc%2eedu|Phenoscape, NESCent, and Department of Biology, University of North Carolina at Chapel Hill|'''}} | ||
+ | {{EventParticipant|Vize|Peter|pvize%40ucalgary%2eca|Department of Biology, University of Calgary|}} | ||
+ | {{EventParticipant|Westerfield|Monte|monte%40uoneuro%2euoregon%2eedu| Phenoscape, Zebrafish Information Network (ZFIN) and Institute of Neuroscience, University of Oregon |'''}} | ||
|} | |} | ||
+ | |||
+ | [[Category:Community]] | ||
+ | [[Category:Events]] | ||
+ | [[Category:Ontology]] |
Latest revision as of 02:21, 21 February 2011
A workshop hosted by the National Evolutionary Synthesis Center (NESCent)
Location and Date
Venue: National Evolutionary Synthesis Center (NESCent) (directions, also see information for visitors)
Date: April 27-28, 2009
Organizers: Paula Mabee, Monte Westerfield, Todd Vision
Introduction
The goal of this workshop is to discuss plans for an RCN (Research Coordination Network) or INTEROP (Community-based Data Interoperability Networks) application to NSF that we would submit in July or August 2009. The grant would provide funds for 3-5 years of meetings and workshops (and in the case of the INTEROP program, implementation to a limited extent) to identify problems and develop methods and plans to describe phenotypes in a much broader range of species.
Specific goals are to be determined by the workshop participants. An initial list includes establishing and maintaining communication among evolutionary biologists and model organism communities developing ontologies, coordinating efforts among the broader ontology community so that these ontologies are interoperable, and methods to align and reason across multi-species ontologies for phenotype and taxonomy. The workshop includes interested members from both the model organism and evolutionary biology communities.
Agenda
Monday, Apr. 27, 2009
Taking stock: Where do we stand? What resources and needs do we have in common? Identify broader community needs for a [Comparative Evolutionary] Phenotype Consortium that are not currently served by individual grants.
Morning: What new ontologies are required? How do existing common ontologies need to be extended?
- 8:00 SHUTTLE FROM HOTEL
- 8:15 Coffee & pastries
- 8:30-9:30 Welcomes from NESCent (Todd Vision) and participant introductions (2-3 minute lightening talks)
- 9:30-9:45 Paula Mabee: Introduction
- 9:45 Breakout groups (4 groups, all 4 questions each):
- Breakout questions: Tools (software), standards, and ontologies
- 1. What are the key gaps in tools to develop your work?
- 2. What are key obstacles to data exchange and data integration?
- 3. What do you perceive as the key ontologies that are lacking?
- 4. What are the gaps in expertise in understanding, developing and applying ontologies in the community?
- 10:45 Coffee
- 11:00-11:45 Second breakout (2 groups, 2 questions each)
- 11:45-12:15 Reports from break-out groups
- 12:15 LUNCH
Afternoon: Annotation and Interoperability
- 1:30 – 2:00: Case study and analysis; interoperability (Monte Westerfield)
- 2:00 – 2:45: Breakout groups:
- Annotation group: What phenotype curation/annotation needs are there that are not adequately met? E.g. software, standards, best-practices, education, syntax, etc.
- Interoperability group 1 (MOD-EvoD): Develop a plan for interoperability between MODs and EvoDs through ontology synchronization and alignment
- Interoperability group 2 (EvoD-EvoD): Develop a plan for interoperability among EvoDs, and with other community resources through alignment, considering the types of driving research questions (similarity searches on function, homology, etc.). What are the most important databases and tools to integrate into this effort?
- 2:45-3:15 Group reports
- 3:15 Coffee break
- 3:30-4:15: Annotation, Interoperability I and II break out groups (different participants)
- 4:15-5:00: Reports from break outs and discussion
- 5:00: Van back to hotel
- 5:30-6:30: Drinks at hotel
- 6:30 Van from hotel to dinner (whole group)
Tuesday, Apr. 27, 2009
Morning: Databases and Trees;
- 8:00 SHUTTLE FROM HOTEL
- 8:15 Coffee & pastries
- 8:45 – 9:30 Break out groups
- Database group: Do we have database needs for annotations from this grant activity? Common database, i.e. a vision to create a community resource for comparative phenotype data?
- Tree group: How does phylogenetic tree inference vs. mapping intersect with the needs of a phenotype consortium?
- Outreach group: What are the priority outreach elements from this grant? How to make these ontologies and annotations (?) available to the broader community? Training (e.g. summer course at Biosynthesis Center, CSH, NESCent, NCESC? Other?); Develop online tutorials? Infrastructure for basics: mailing list, meeting announcements, etc.
- 9:30-10:00 Reports from break out groups
- 10:00-10:15 Coffee
- 10:15-10:30: Decisions on who will write up break out group ideas
- 10:30-11:30: Writing
- 11:30-12:00: Action items, plans, preliminary coordination of grant proposal
- 12:00 Lunch, participants leave
Logistics
- For long-distance participants, the hotel is the Millennium Hotel (2800 Campus Walk Ave, Durham, NC 27705; tel. (919) 383-8575)
- For dining & entertainment, NESCent is right across from Ninth Street
- For the venue, NESCent is in the historic Erwin Mills building (directions)
Reading
- Within the Phenoscape project, we have been tagging interesting references about phenotype and taxonomy ontologies by using the tag "phenoscape" on Connotea. Everyone is welcome to suggest references by using this tag.
Final report
- The final report from this workshop summarizes the participants views as the specific research questions to be answered and thus goals to be achieved through a community‐based grant. Break-out groups provided perspective on the questions below.
1. What are the key gaps in tools to develop your work? 2. What are key obstacles to data exchange and data integration? 3. What do you perceive as the key ontologies that are lacking? 4. What are the gaps in expertise in understanding, developing and applying ontologies in the community?
Participants
Members of Phenoscape are in bold font.
Name | Institution |
---|---|
Judy Blake | The Jackson Laboratory |
Jonathan Coddington | Department of Entomology, Smithsonian Institution |
Lindsay Cowell | Duke University Medical Center |
Andy Deans | Hymenoptera Tree of Life and Department of Entomology, North Carolina State University |
Betsy Dumont | Department of Biology, Univerity of Massachusetts, Amherst |
Eva Huala | The Arabidopsis Information Resource |
Hilmar Lapp | Phenoscape and NESCent |
Suzi Lewis | Berkeley Bioinformatics and Ontology Project |
Paula Mabee | Phenoscape and Department of Biology, University of South Dakota |
Anne Maglia | Missouri University of Science and Technology |
Austin Mast | Florida State University |
Peter Midford | Phenoscape and Dept. of Ecology and Evolutionary Biology, University of Kansas |
Cyndy Parr | Smithsonian Institution and Encyclopedia of Life |
Greg Riccardi | College of Information, Florida State University |
Paul Sereno | University of Chicago |
Arlin Stoltzfus | Center for Advanced Research in Biotechnology, University of Maryland |
Todd Vision | Phenoscape, NESCent, and Department of Biology, University of North Carolina at Chapel Hill |
Peter Vize | Department of Biology, University of Calgary |
Monte Westerfield | Phenoscape, Zebrafish Information Network (ZFIN) and Institute of Neuroscience, University of Oregon |